Autoimmune Disorders in Dogs: When the Immune System Turns Against the Body
Autoimmune disorders in dogs happen when the immune system wrongly attacks the dog’s own body. They can affect the skin, blood, joints, kidneys and other organs. Common conditions include immune-mediated haemolytic anaemia (IMHA), immune-mediated thrombocytopenia (IMTP), pemphigus, systemic lupus erythematosus (SLE) and immune-mediated polyarthritis (IMPA). Signs of autoimmune disease in dogs vary but often include lethargy, pale gums, bruising or bleeding, skin sores, hair loss, joint pain and loss of appetite. Diagnosis uses blood and urine tests, imaging, special immune tests and sometimes biopsy. Treatment for autoimmune dogs typically involves immunosuppressive medicines such as prednisolone, azathioprine or ciclosporin, plus supportive care like transfusions, fluids, antibiotics and pain relief. Many dogs need long-term medication and regular monitoring, and some go into good control while others have relapses. Seek urgent veterinary care if your dog collapses, bleeds heavily, has trouble breathing or stops eating; early veterinary assessment improves the chance of a good quality of life.